Statins in Variant Angina

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Statins in Variant Angina

Variant angina pectoris (VAP) is a form of angina pectoris that shows transient ST-segment elevation on electrocardio-gram during an attack of chest pain and is caused by coronary artery spasm. Although the pathogenesis of coronary artery spasm has not been fully elucidated, endothelial dysfunction and enhanced vascular smooth muscle contractility play major roles in the pathogenesis of coronar...

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Arrhythmias in Variant Angina Pectoris

Twenty-six patients with variant angina pectoris (VAP) were studied 1) to determine whether the degree of ST-segment elevation and R-wave changes correlate with the development of arrhythmias; and 2) to evaluate the relationship between the prevalence of arrhythmias, the severity of coronary artery disease, left ventricular function and wall motion. Serious arrhythmias were found in 12 patients...

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"Variant" Angina Pectoris

Classical angina pectoris is characterized by recurrent attacks of retrosternal pain brought on by effort and emotion and relieved by rest and the administration of nitroglycerin. It is well known that this classical syndrome has many variations and modifications. In 1959, and again in 1960, Prinzmetal and his colleagues described what they called a "variant form of angina pectoris." According ...

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Effects of intravenous prostacyclin in variant angina.

A lack in prostacyclin (PGI2) production due to atherosclerosis may play a role in the pathophysiology of some of the clinical manifestations of ischemic heart disease and in particular, of coronary vasospasm. We therefore evaluated the effects of i.v. PGI2 in nine patients with variant angina and six normal volunteers. In normal subjects, PGI2 (2.5, 5, 10 and 20 micrograms/kg/min) had signific...

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Syncope in association with Prinzmetal variant angina.

A case of Prinzmetal variant angina with transient complete atrioventricular block and syncopal episodes following an anteroseptal myocardial infarction is described. The syncopal attacks were not prevented by demand cardiac pacing and were presumably caused by transient severe ischaemia of the left ventricle, with a consequent reduction in cardiac output. The left ventriculogram showed a large...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Ultrasound

سال: 2013

ISSN: 1975-4612,2005-9655

DOI: 10.4250/jcu.2013.21.2.56